氧化低密度脂蛋白/Human ox-LDL说明书-分析方法-资讯-生物在线
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氧化低密度脂蛋白/Human ox-LDL说明书

作者：上海钰博生物科技有限公司 2023-03-29T00:00 (访问量:406)

 Human ox-LDL

氧化低密度脂蛋白

英文名称 Human ox-LDL
中文名称 氧化低密度脂蛋白
别    名 ox-LDL: LDL (Copper oxidized); Cu2SO4 oxidized low density lipoprotein; oxidized low density lipoprotein; Low density lipoprotein; MDA oxidized LDL; MDA oxidized low density lipoprotein; Human ox-LDL   氧化型低密度脂蛋白;
Specific References  (7)     |     bs-1698P has been referenced in 7 publications.
111 [IF=3.466] Zhang et al. H19 knockdown suppresses proliferation and induces apoptosis by regulating miR-148b/WNT/β-catenin in ox-LDL -stimulated vascular smooth muscle cells. (2018) J.Biomed.Sci. 25:11  other ;  Human.  222
111 [IF=3.514] Su Q et al. Pinocembrin protects endothelial cells from oxidized LDL-induced injury.Cytokine. 2018 Nov;111:475-480.  Other ;  
111 [IF=3.309] Ye J et al. LncRBA GSA5, up-regulated by ox-LDL, aggravates inflammatory response and MMP expression in THP-1 macrophages by acting like a sponge for miR-221.Exp Cell Res. 2018 Aug 15;369(2):348-355.  Other ;  
111 [IF=3.647] Yi Zhou et al. Long non-coding RNA MIAT/miR-148b/PAPPA axis modifies cell proliferation and migration in ox-LDL-induced Human aorta vascular smooth muscle cells. Life Sci. 2020 Sep 1;256:117852.  Other ;  Human.  222
111 [IF=2.1] Heng-Jing Hu. et al. Hydrogen sulfide improves ox‑LDL‑induced expression levels of Lp‑PLA2 in THP‑1 monocytes via the p38MAPK pathway. Mol Med Rep. 2021 May;23(5):1-10  Other ;  
 
111 [IF=1.785] Huiqiong Jiang. et al. MicroRNA‑301a‑3p increases oxidative stress, inflammation and apoptosis in ox‑LDL‑induced HUVECs by targeting KLF7. Exp Ther Med. 2021 Jun;21(6):1-8  WB,FC ;  Human.  222
111 [IF=6.986] Yang, Yilin. et al. Knockdown of lncRNA H19 alleviates ox-LDL-induced HCAECs inflammation and injury by mediating miR-20a-5p/HDAC4 axis. INFLAMM RES. 2022 Jul;:1-13  
 
 
性    状 Liquid
浓    度 >1.0 mg/ml
物    种 Human
序    列 Purified native protein
内毒素 Not analyzed
活性 Not tested
缓 冲 液 10 mM PBS(pH=7.4) with 0.01 μM EDTA.
保存条件 Store at 4°C for 8 weeks. Avoid freeze.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.

来源：正常人血浆中分离获得，经铜离子氧化人源血浆低密度脂蛋白;。
纯度：98%，(琼脂糖凝胶电泳)
注意事项：
1. 长时间的储存后可能会产生沉淀，这种现象属于正常情况。将溶液放入离心管中离心2分钟将聚合物除去即可。
2. 高密度脂蛋白相当不稳定，提前计划你的实验，使用新鲜的材料，建议实验时最好现用现配，采用新鲜配置工作液

本产品仅供科研使用.请勿用于医药,不能用于临床治疗诊断使用！

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