WWP1抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
WWP1抗体

WWP1抗体

商家询价

产品名称: WWP1抗体

英文名称: WWP1Antibody

产品编号: XY13587-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
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 WWP1抗体Applications

In-house applications ELISA, WB, IP, IF     Application not tested? Please see our Guarantee.
Published applications IHC, WB Publications 2 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, mouse
Images
Prev1NextView more validation data
  • 13587-1-AP;PC-3 cellsPC-3 cells were subjected to SDS PAGE followed by western blot with 13587-1-AP(WWP1 antibody) at dilution of 1:300
  • 13587-1-AP;PC-3 cellsIP Result of anti-WWP1 (IP:13587-1-AP, 4ug; Detection:13587-1-AP 1:300) with PC-3 cells lysate 1040ug.
  • 13587-1-AP;PC-3 cellsImmunofluorescent analysis of ( -20℃ Ethanol ) fixed PC-3 cells using 13587-1-AP( WWP1 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in PC-3 cells
Positive IP detected in PC-3 cells
Positive IF detected in PC-3 cells
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:1000
IF : 1:20-1:200
 WWP1抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen WWP1 fusion protein ag3582 Full name WW domain containing E3 ubiquitin protein ligase 1
Calculated molecular
weight
922aa,105 kDa Observed molecular 
weight
95 kDa
GenBank accession 
number
BC036065 Gene ID (NCBI) 11059
Gene symbol WWP1 Synonyms AIP5, DKFZp434D2111, hSDRP1, Tiul1, WW domain containing protein 1, WWP1
Background WWP1抗体

WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) is a multifunction protein containing an N-terminal C2 domain, four tandem WW domains for substrate binding, and a C-terminal catalytic HECT domain for ubiquitin transferring. It is also named as AIP5, Tiul1. WWP1 regulates a variety of cellular biological processes including protein trafficking and degradation, signaling, transcription, and viral budding. WWP1 has been implicated in several diseases, such as cancers, infectious diseases, neurological diseases, and aging(PMID:22051607). It has 6 isoforms produced by alternative splicing. WWP1抗体

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