Anti-CD209 Polyclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司
Anti-CD209 Polyclonal Antibody

Anti-CD209 Polyclonal Antibody

商家询价

产品名称: Anti-CD209 Polyclonal Antibody

英文名称: Anti-CD209 Polyclonal Antibody

产品编号: K002796P

产品价格: null

产品产地: 北京

品牌商标: Solarbio

更新时间: 2025-12-22T13:19:53

使用范围:

北京索莱宝科技有限公司
  • 联系人 : 索莱宝-龚思雨
  • 地址 : 北京市北京经济技术开发区环科中路16号26幢3层301
  • 邮编 :
  • 所在区域 : 北京
  • 电话 : 181****6239 点击查看
  • 传真 : 点击查看
  • 邮箱 : 3193328036@qq.com
  • 二维码 : 点击查看

Anti-CD209 Polyclonal Antibody

品牌:solarbio | 货号:K002796P
商品货号:商品品牌:规格基本售价:选择规格
K002796P-50ulsolarbio50ul960.00元
K002796P-100ulsolarbio100ul1600.00元
英文名称Anti-CD209 Polyclonal Antibody
别名CDSIGN;CLEC4L;DC-SIGN;DC-SIGN1
应用WB
稀释比例WB 1:200-500.
交叉反应Human Mouse Rat
蛋白分子量46kDa
Gene ID30835
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human CD209
性状液体
Public Immunogen RangeRecombinant protein of human CD209
Subcellular LocationsCell membrane Secreted Single-pass type II membrane protein
Swiss ProtQ9NNX6
克隆类型Polyclonal Antibody
背景资料This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332; often referred to as L-SIGN). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.