分子量：Calculated MW: 62kDa
Observed MW: 74KDa

细胞定位：Cytoplasm, Nucleus, perinuclear region

稀释方法：WB 1:500 - 1:2000

总结：The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]