FITC标记的核仁蛋白12抗体
产品名称： FITC标记的核仁蛋白12抗体
英文名称： Anti-NOL12/NOP25/FITC
产品编号： HZ-19309R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-NOL12/NOP25/FITC Conjugated antibody
FITC标记的核仁蛋白12抗体
| 英文名称 | Anti-NOL12/NOP25/FITC |
| 中文名称 | FITC标记的核仁蛋白12抗体 |
| 别 名 | C78541; dJ37E16.7; FLJ34609; MGC3731; Nol12; NOL12_HUMAN; Nop25; Nucleolar protein 12; Nucleolar protein of 25 kDa. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 25kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NOL12/NOP25 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Nop25 is a 213 amino acid protein that localizes to the nucleolus and is thought to bind to 28S rRNA, possibly playing a role in the processing of rRNA molecules and in the subsequent assembly and maturation of ribosomes. The gene encoding Nop25 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias. Function: May bind to 28S rRNA. Subcellular Location: Nucleus > nucleolus. Similarity: Belongs to the RRP17 family. Database links: Entrez Gene: 79159 Human Entrez Gene: 97961 Mouse Entrez Gene: 362955 Rat SwissProt: Q9UGY1 Human SwissProt: Q8BG17 Mouse SwissProt: Q5D1Z3 Rat Unigene: 632778 Human Unigene: 157216 Mouse Unigene: 17454 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Nop25是定位于核仁的213个氨基酸蛋白，被认为与28S rRNA结合，可能在rRNA分子的加工以及随后的核糖体的组装和成熟中发挥作用。编码Nop25的基因编码到人类22号染色体上，它含有500个以上的基因，是第二个最小的人类染色体。一些基因突变与22号染色体有关，这些基因与Phelan-McDermid综合征、神经纤维瘤病2型、孤独症和精神分裂症有关。此外，染色体9和22之间的易位可能导致费城染色体的形成和随后产生新的融合蛋白BCR-Abl，一种在几种类型的白血病中发现的有效的细胞增殖激活剂。