FITC标记的结核分枝杆菌分泌性蛋白ESAT6抗体
产品名称： FITC标记的结核分枝杆菌分泌性蛋白ESAT6抗体
英文名称： Anti-ESAT6/FITC
产品编号： HZ-13107R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ESAT6/FITC Conjugated antibody
FITC标记的结核分枝杆菌分泌性蛋白ESAT6抗体
| 英文名称 | Anti-ESAT6/FITC |
| 中文名称 | FITC标记的结核分枝杆菌分泌性蛋白ESAT6抗体 |
| 别 名 | 6 kDa early secretory antigenic target; 6 kDa early secretory antigenic target ESXA; ESAT 6; esaT6; ESXA; ESXA_MYCTU; ESAT-6. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 细菌及病毒 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mycobacterium tuberculosis, Mycobacterium szulgai, Mycobacte |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 10kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Mycobacterium tuberculosis ESAT6 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Mycobacterium tuberculosis is a slow-growing obligate aerobic bacillus that causes most cases of tuberculosis (TB). It is a small, rod-like microbe that can withstand weak disinfectants and survive in a dry state for weeks, but can only grow within a host organism. M. tuberculosis has a thick waxy cell wall that is responsible for the typical caseous granuloma formation in tuberculosis. ESAT6 is a protein secreted by M. tuberculosis that induces a strong immune response in infected organisms, making it a strong candidate for the development of a vaccine against tuberculosis. ESAT6 may also be useful in the detection of the disease. Deletion of the ESAT6 gene leads to the loss of virulence of M. tuberculosis. Function: The ESAT6 antigen from Mycobacterium tuberculosis is a dominant target for cell mediated immunity in the early phase of tuberculosis (TB) in TB patients as well as in various animal models. ESAT6 is not found in M. bovis BCG. Its function is not known but it elicits high level of IFN-gamma from memory effector cells during the first phase of a protective immune response. Subcellular Location: Secreted Similarity: Belongs to the ESAT-6 (esx) family. Database links: Entrez Gene: 886209 MYCTUSwissProt: P9WNK6 MYCTU Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
结核分枝杆菌是一种生长缓慢的专性好氧芽孢杆菌，引起大多数结核病（TB）。它是一种小的杆状微生物，能够经受住弱消毒剂并在干燥状态下存活数周，但是只能在宿主生物体内生长。结核分枝杆菌有一层厚的蜡状细胞壁，负责肺结核中典型的干酪性肉芽肿形成。ESAT6是由结核分枝杆菌分泌的蛋白质，在受感染的生物体中诱导强烈的免疫应答，使其成为开发抗结核疫苗的强有力候选者。ESAT6也可用于疾病的检测。缺失的ESAT6基因导致结核分枝杆菌的毒力损失。