Anti-CASP3 Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K101291P-50ul	solarbio	50ul	960.00元
K101291P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-CASP3 Polyclonal Antibody
别名	CPP32;CPP32B;SCA-1;SREBP cleavage activity 1;Cysteine protease CPP32
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:80.
交叉反应	Human Mouse
蛋白分子量	31kDa
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human CASP3
性状	液体
Public Immunogen Range	A synthetic peptide of human CASP3
Subcellular Locations	Cytoplasm
Swiss Prot	P42574
克隆类型	Polyclonal Antibody
背景资料	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-\|-Gly-217 bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.