CARD11 polyclonal antibody
产品名称： CARD11 polyclonal antibody
英文名称： CARD11 polyclonal antibody
产品编号： PAB14607
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CARD11.
- Immunogen:
- A synthetic peptide corresponding to amino acids 1072-1087 of human CARD11.
- Sequence:
- CEKNIKRFRKLLPRPE
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In serum (50% glycerol, 0.025% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:100-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B.
Bertin J, Wang L, Guo Y, Jacobson MD, Poyet JL, Srinivasula SM, Merriam S, DiStefano PS, Alnemri ES.J Biol Chem. 2001 Apr 13;276(15):11877-82. Epub 2001 Jan 12.
- Application Image
- ELISA
- Entrez GeneID:
- 84433
- Protein Accession#:
- NP_115791
- Gene Name:
- CARD11
- Gene Alias:
- BIMP3,CARMA1,MGC133069
- Gene Description:
- caspase recruitment domain family, member 11
- Omim ID:
- 607210
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq
- Other Designations:
- OTTHUMP00000024641,bcl10-interacting maguk protein 3,card-maguk protein 1
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