分子量：Calculated MW: 59kDa/66kDa
Observed MW: 67kDa

细胞定位：Cytoplasm, Nucleus

稀释方法：WB 1:500 - 1:1000
IHC 1:50 - 1:100
IF 1:20 - 1:100

总结：DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development.  The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues.  DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro.  Two isoforms of DYRK2 have been isolated.  The predominant isoform, isoform 1, lacks a 5' terminal insert.