TREM2 monoclonal antibody, clone 2B5
产品名称： TREM2 monoclonal antibody, clone 2B5
英文名称： TREM2 monoclonal antibody, clone 2B5
产品编号： MAB2056
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant TREM2.
- Immunogen:
- Recombinant protein corresponding to amino acids 19-161 of human TREM2.
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Isotype:
- IgG3, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria.
N'Diaye EN, Branda CS, Branda SS, Nevarez L, Colonna M, Lowell C, Hamerman JA, Seaman WE.J Cell Biol. 2009 Jan 26;184(2):215-23.
- 2.
- Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation.
Piccio L, Buonsanti C, Cella M, Tassi I, Schmidt RE, Fenoglio C, Rinker J 2nd, Naismith RT, Panina-Bordignon P, Passini N, Galimberti D, Scarpini E, Colonna M, Cross AH.Brain. 2008 Nov;131(Pt 11):3081-91. Epub 2008 Sep 12.
- Applications
- Western Blot
- Cell lysates of HeLa (lane 1), MCF-7 (lane 2), LNCaP (lane 3) and mouse brain (lane 4) (30 ug) were resolved by SDS-PAGE and probed with TREM2 monoclonal antibody, clone 2B5 (Cat # MAB2056) (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 54209
- Protein Accession#:
- NP_061838
- Gene Name:
- TREM2
- Gene Alias:
- TREM-2,Trem2a,Trem2b,Trem2c
- Gene Description:
- triggering receptor expressed on myeloid cells 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). [provided by RefSeq
- Other Designations:
- OTTHUMP00000016368,OTTHUMP00000039771,triggering receptor expressed on monocytes 2,triggering receptor expressed on myeloid cells 2a