MAPK7 polyclonal antibody
产品名称： MAPK7 polyclonal antibody
英文名称： MAPK7 polyclonal antibody
产品编号： PAB2891
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MAPK7.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MAPK7.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Primary structure of BMK1: a new mammalian map kinase.
Lee JD, Ulevitch RJ, Han J.Biochem Biophys Res Commun. 1995 Aug 15;213(2):715-24.
- 2.
- Components of a new human protein kinase signal transduction pathway.
Zhou G, Bao ZQ, Dixon JE.J Biol Chem. 1995 May 26;270(21):12665-9.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of MAPK7 polyclonal antibody (Cat # PAB2891) in HL-60 cell lysate. MAPK7 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with MAPK7 polyclonal antibody (Cat # PAB2891) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 5598
- Protein Accession#:
- Q13164
- Gene Name:
- MAPK7
- Gene Alias:
- BMK1,ERK4,ERK5,PRKM7
- Gene Description:
- mitogen-activated protein kinase 7
- Omim ID:
- 602521
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq
- Other Designations:
- BMK1 kinase,OTTHUMP00000065906,big MAP kinase 1,extracellular-signal-regulated kinase 5
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