分子量：Calculated MW: 70kDa
Observed MW: 82kDa

细胞定位：Cell junction, Cell membrane, Cell projection, Multi-pass membrane protein, Perikaryon, dendrite, dendritic spine, postsynaptic cell membrane, synapse

稀释方法：WB 1:500 - 1:2000
IHC 1:50 - 1:200

总结：Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.