Ticam1 polyclonal antibody
产品名称: Ticam1 polyclonal antibody
英文名称: Ticam1 polyclonal antibody
产品编号: PAB0317
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of Ticam1.
- Immunogen:
- A synthetic peptide corresponding to amino acids 143-158 of mouse Ticam1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.2% gelatin, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Absence of SHIP-1 Results in Constitutive Phosphorylation of Tank-Binding Kinase 1 and Enhanced TLR3-Dependent IFN-{beta} Production.
Gabhann JN, Higgs R, Brennan K, Thomas W, Damen JE, Ben Larbi N, Krystal G, Jefferies CA.J Immunol. 2010 Mar 1;184(5):2314-20. Epub 2010 Jan 25.
- 2.
- Renal collecting duct epithelial cells react to pyelonephritis-associated Escherichia coli by activating distinct TLR4-dependent and -independent inflammatory pathways.
Chassin C, Goujon JM, Darche S, du Merle L, Bens M, Cluzeaud F, Werts C, Ogier-Denis E, Le Bouguenec C, Buzoni-Gatel D, Vandewalle A.J Immunol. 2006 Oct 1;177(7):4773-84.
- 3.
- Transforming growth factor-beta differentially inhibits MyD88-dependent, but not TRAM- and TRIF-dependent, lipopolysaccharide-induced TLR4 signaling.
Naiki Y, Michelsen KS, Zhang W, Chen S, Doherty TM, Arditi M.J Biol Chem. 2005 Feb 18;280(7):5491-5. Epub 2004 Dec 28.
- Entrez GeneID:
- 148022
- Gene Name:
- TICAM1
- Gene Alias:
- MGC35334,PRVTIRB,TICAM-1,TRIF
- Gene Description:
- toll-like receptor adaptor molecule 1
- Omim ID:
- 607601
- Gene Ontology:
- Hyperlink
- Gene Summary:
- TRIF, or TICAM1, is a Toll/IL1R (MIM 147810) (TIR) domain-containing adaptor molecule, like MYD88 (MIM 602170) and TIRAP (MIM 606252), that induces interferon-beta (IFNB; MIM 147640), specifically interacts with TLR3 (MIM 603029), and activates nuclear factor kappa-B (NFKB; see MIM 164011).[supplied by OMIM
- Other Designations:
- TIR domain containing adaptor inducing interferon-beta,TIR domain-containing adaptor molecule 1
- Gene Pathway