KCNJ11 (Human) Recombinant Protein (Q01)
产品名称： KCNJ11 (Human) Recombinant Protein (Q01)
英文名称： KCNJ11 (Human) Recombinant Protein (Q01)
产品编号： H00003767-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human KCNJ11 partial ORF ( NP_000516.3, 301 a.a. - 390 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- RTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLEALTLASARGPLRKRSVPMAKAKPKFSISPDSLS
- Theoretical MW (kDa):
- 35.64
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 3767
- GeneBank Accession#:
- NM_000525
- Protein Accession#:
- NP_000516.3
- Gene Name:
- KCNJ11
- Gene Alias:
- BIR,HHF2,IKATP,KIR6.2,MGC133230,PHHI,TNDM3
- Gene Description:
- potassium inwardly-rectifying channel, subfamily J, member 11
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). [provided by RefSeq
- Other Designations:
- ATP-sensitive inward rectifier potassium channel 11,beta-cell inward rectifier subunit,inwardly rectifying potassium channel KIR6.2,potassium inwardly-rectifying channel J11
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Atherosclerosis
- Atherosclerosis
- Birth Weight
- Calcinosis
- Carcinoma
- Cardiovascular Diseases
- Coronary Artery Disease
- Coronary Disease
- Death, Sudden, Cardiac
- Diabetes Complications
- Diabetes Mellitus
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetes, Gestational
- Diabetes, type 1
- Diabetic Angiopathies
- Diabetic Nephropathies