HSPA5 monoclonal antibody
产品名称： HSPA5 monoclonal antibody
英文名称： HSPA5 monoclonal antibody
产品编号： MAB8736
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant HSPA5.
- Immunogen:
- Recombinant protein corresponding to C-terminus residues of human HSPA5.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody is specific to HSPA5.
- Form:
- Liquid
- Purification:
- Protein G purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, pH 7.4 (0.02% sodium azide, 1% BSA, 50% glycerol)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:100-1:2000)
ELISA (1:5000-1:20000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 3309
- Gene Name:
- HSPA5
- Gene Alias:
- BIP,FLJ26106,GRP78,MIF2
- Gene Description:
- heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
- Omim ID:
- 138120
- Gene Ontology:
- Hyperlink
- Gene Summary:
- When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM
- Other Designations:
- Heat-shock 70kD protein-5 (glucose-regulated protein, 78kD),OTTHUMP00000022124,heat shock 70kD protein 5 (glucose-regulated protein, 78kD),heat shock 70kDa protein 5
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Bipolar Disorder
- Carcinoma, Hepatocellular
- Cognition
- Disease Susceptibility
- Genetic Predisposition to Disease
- Hepatitis B
- Hepatitis B, Chronic
- Infection
- Kidney Failure, Chronic
- Liver Neoplasms
- Parkinson Disease
- Parkinson disease
- Schizophrenia
- Schizophrenia
- Stress, Psychological