CSE1L polyclonal antibody
产品名称： CSE1L polyclonal antibody
英文名称： CSE1L polyclonal antibody
产品编号： PAB3748
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CSE1L.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CSE1L.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Src phosphorylates Cas on tyrosine 253 to promote migration of transformed cells.
Goldberg GS, Alexander DB, Pellicena P, Zhang ZY, Tsuda H, Miller WT.J Biol Chem. 2003 Nov 21;278(47):46533-40. Epub 2003 Sep 11.
- 2.
- CSE1L/CAS: its role in proliferation and apoptosis.
Behrens P, Brinkmann U, Wellmann A.Apoptosis. 2003 Jan;8(1):39-44.
- 3.
- CAS/CSE 1 stimulates E-cadhrin-dependent cell polarity in HT-29 human colon epithelial cells.
Jiang MC, Liao CF, Tai CC.Biochem Biophys Res Commun. 2002 Jun 21;294(4):900-5.
- Entrez GeneID:
- 1434
- Protein Accession#:
- NP_001307;P55060
- Gene Name:
- CSE1L
- Gene Alias:
- CAS,CSE1,MGC117283,MGC130036,MGC130037,XPO2
- Gene Description:
- CSE1 chromosome segregation 1-like (yeast)
- Omim ID:
- 601342
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq
- Other Designations:
- CSE1 chromosome segregation 1-like protein,OTTHUMP00000043373,cellular apoptosis susceptibility protein,chromosome segregation 1-like,importin-alpha re-exporter