ACTB polyclonal antibody
产品名称： ACTB polyclonal antibody
英文名称： ACTB polyclonal antibody
产品编号： PAB7880
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ACTB.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human ACTB.
- Host:
- Rabbit
- Reactivity:
- Chicken, Human, Mouse, Rat
- Specificity:
- This sequence is identical to similar regions in all four a actins, as well as in g actin, and is well conserved in actins from most eukaryotic species.
- Form:
- Liquid
- Storage Buffer:
- In PBS (50% glycerol, 1 mg/mL BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:2000)
Immunocytochemistry (1:50)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Phosphorylation of actin Tyr-53 inhibits filament nucleation and elongation and destabilizes filaments.
Liu X, Shu S, Hong MS, Levine RL, Korn ED.Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13694-9. Epub 2006 Aug 30.
- 2.
- Actin-binding proteins.
Winder SJ, Ayscough KR.J Cell Sci. 2005 Feb 15;118(Pt 4):651-4.
- 3.
- Actin tyrosine dephosphorylation by the Src homology 1-containing protein tyrosine phosphatase is essential for actin depolymerization after membrane IgM cross-linking.
Baba T, Fusaki N, Shinya N, Iwamatsu A, Hozumi N.J Immunol. 2003 Apr 1;170(7):3762-8.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of mouse C2C12 cells untreated (lane 1), or treated with pervanadate (1 mM) for 30 min (lane 2). The blot was probed with ACTB polyclonal antibody (Cat # PAB7880).
- Entrez GeneID:
- 60
- Protein Accession#:
- P60709
- Gene Name:
- ACTB
- Gene Alias:
- PS1TP5BP1
- Gene Description:
- actin, beta
- Omim ID:
- 102630
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq
- Other Designations:
- PS1TP5-binding protein 1,actin, cytoplasmic 1,beta actin,beta cytoskeletal actin
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