FITC标记的磷酸化乳腺癌易感基因相互作用蛋白1抗体
产品名称： FITC标记的磷酸化乳腺癌易感基因相互作用蛋白1抗体
英文名称： Anti-phospho-BACH1 (Ser990)/FITC
产品编号： HZ-5226R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-phospho-BACH1 (Ser990)/FITC Conjugated antibody
FITC标记的磷酸化乳腺癌易感基因相互作用蛋白1抗体
| 英文名称 | Anti-phospho-BACH1 (Ser990)/FITC |
| 中文名称 | FITC标记的磷酸化乳腺癌易感基因相互作用蛋白1抗体 |
| 别 名 | BACH 1; BRIP1; BACH-1; BRAC 1 Associated C Terminal Helicase 1; BRCA 1 Interacting Protein 1; BRCA1 binding helicase like protein BACH1; BRCA1 interacting protein C terminal helicase 1; BRIP 1; BRIP-1; FANCJ; ATP dependent RNA helicase BRIP1; Fanconi anemia group J protein; FLJ90232; MGC126521; MGC126523; OF antibody Protein FACJ; FANCJ_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 产品类型 | 磷酸化抗体 |
| 研究领域 | 肿瘤 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Cow, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 141kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human BRIP1 around the phosphorylation site of Ser990 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009]. Function: Transcriptional regulator that acts as repressor or activator. Binds, in-vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK. Subcellular Location: Nucleus. Similarity: Belongs to the bZIP family. CNC subfamily. Contains 1 BTB (POZ) domain. Contains 1 bZIP domain. Database links: Entrez Gene: 83990 Human Omim: 605882 Human SwissProt: Q9BX63 Human Unigene: 128903 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码属于CAN'领型的基本区域亮氨酸拉链因子家族（CNC BZIP）的转录因子。编码的蛋白质含有广泛的复合物、TrAMTrAb、BRIC-A BRAC/痘病毒和锌指（BTB/POZ）结构域，这是CNC BZIP家族成员的非典型性。这些BTB/POZ结构域有助于蛋白质-蛋白质相互作用和同源和/或异质低聚物的形成。当该编码蛋白与MafK形成异源二聚体时，它起到MAF识别元件（MARE）的阻遏作用，并抑制转录。该基因已鉴定出多个交替剪接转录变体。[ RefSeq，2009年5月提供]。