ACHE monoclonal antibody
产品名称： ACHE monoclonal antibody
英文名称： ACHE monoclonal antibody
产品编号： MAB0212
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic peptide of ACHE.
- Immunogen:
- A synthetic peptide corresponding to C-terminus 10 amino acids of human ACHE.
- Host:
- Mouse
- Reactivity:
- Bovine, Human
- Specificity:
- This antibody is specific to brain ACHE and does not recognize ACHE from erythrocytes. This antibody can thus distinguish between mammalian brain ACHE and erythrocyte ACHE. Weak cross-reactivity with Torpedo marmorata AChE but none with ACHE from electric eel or human BtChE.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In 10 mM phosphate buffer, 500 mM NaCl, pH 7.4 (15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Avoid prolonged exposure to light.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Western Blot
- ELISA
- Entrez GeneID:
- 43
- Gene Name:
- ACHE
- Gene Alias:
- ARACHE,N-ACHE,YT
- Gene Description:
- acetylcholinesterase (Yt blood group)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq
- Other Designations:
- acetylcholinesterase,apoptosis-related acetylcholinesterase
- Gene Pathway