ESR1 polyclonal antibody
产品名称： ESR1 polyclonal antibody
英文名称： ESR1 polyclonal antibody
产品编号： PAB18472
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ESR1.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding S104/S106 of human ESR1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody is specific to ESR1.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
ELISA (1:20000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells.
Liu Y, Wu C, Galaktionov K.J Biol Chem. 2004 Feb 6;279(6):4507-14. Epub 2003 Nov 3.
- 2.
- Inhibition of cdk2 activating phosphorylation by mevastatin.
Ukomadu C, Dutta A.J Biol Chem. 2003 Feb 14;278(7):4840-6. Epub 2002 Dec 9.
- 3.
- Kinetic mechanism of activation of the Cdk2/cyclin A complex. Key role of the C-lobe of the Cdk.
Morris MC, Gondeau C, Tainer JA, Divita G.J Biol Chem. 2002 Jun 28;277(26):23847-53. Epub 2002 Apr 16.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of extracts from MCF-7 cells, untreated or treated with Estradio, using ESR1 polyclonal antibody (Cat # PAB18472).
Peptide "+" means "peptide blocking".
- Entrez GeneID:
- 2099
- Protein Accession#:
- P03372
- Gene Name:
- ESR1
- Gene Alias:
- DKFZp686N23123,ER,ESR,ESRA,Era,NR3A1
- Gene Description:
- estrogen receptor 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq
- Other Designations:
- OTTHUMP00000017718,OTTHUMP00000017719,estrogen receptor alpha
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