FITC标记的SYCE1蛋白抗体
产品名称: FITC标记的SYCE1蛋白抗体
英文名称: Anti-SYCE1/FITC
产品编号: HZ-4323R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SYCE1/FITC Conjugated antibody
FITC标记的SYCE1蛋白抗体
英文名称 | Anti-SYCE1/FITC |
中文名称 | FITC标记的SYCE1蛋白抗体 |
别 名 | bA108K14.6; C10orf94; Cancer/testis antigen 76; CT76; RP11-108K14.6; Syce1; SYCE1_HUMAN; Synaptonemal complex central element protein 1. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 细胞周期蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 40kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 2mg/1ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SYCE1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene encodes a member of the synaptonemal complex, which links homologous chromosomes during prophase I of meiosis. The tripartite structure of the complex is highly conserved amongst metazoans. It consists of two lateral elements and a central region formed by transverse elements and a central element. The protein encoded by this gene localizes to the central element and is required for initiation and elongation of the synapsis. Allelic variants of this gene have been associated with premature ovarian failure and spermatogenic failure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016] Function: Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complexe assembly, stabilization and recombination. Subcellular Location: Nucleus. Chromosome. Associates with chromatin. In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed. Colocalizes with SYCE2 in the central elements. Similarity: Belongs to the SYCE family. Database links: Entrez Gene: 93426 Human Omim: 611486 Human SwissProt: Q8N0S2 Human Unigene: 553795 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
这个基因编码联会复合体的一个成员,在减数分裂前期I它连接着同源染色体。该复合物的三重结构在后生动物中高度保守。它由两个横向单元和一个由横向单元和一个中心单元构成的中心区域组成。该基因编码的蛋白定位于中央元件,并且是突触起始和伸长所必需的。该基因的等位基因变异与卵巢早衰和生精功能衰竭有关。选择性剪接导致多个转录变体。[ RefSeq,2016月11日]