产品概述：Purified recombinant protein of Human transthyretin (TTR), Gly21-End, Tag Free, expressed in E. coli, 50ug

蛋白长度：A DNA sequence encoding the region(Gly21-End) of TTR

表达系统：E. coli

种属：Human

标签类型：Tag Free

分子量：16 kDa

通用名：TTR

总结：This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017]

形式：Liquid

浓度：>50ug/ml as determined by microplate BCA method

纯度：> 99% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：1 x PBS, pH7.4, 10% glycerol.

别名：ATTR; CTS; CTS1; HEL111; HsT2651; PALB; TBPA; TTN