FITC标记的动力蛋白轻链Tctex-3抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的动力蛋白轻链Tctex-3抗体

FITC标记的动力蛋白轻链Tctex-3抗体

商家询价

产品名称: FITC标记的动力蛋白轻链Tctex-3抗体

英文名称: Anti-DYNLT3/FITC

产品编号: HZ-14472R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-DYNLT3/FITC Conjugated antibody 

 

FITC标记的动力蛋白轻链Tctex-3抗体
英文名称 Anti-DYNLT3/FITC
中文名称 FITC标记的动力蛋白轻链Tctex-3抗体
别    名 2310075M16Rik; AU042796; DYLT3_HUMAN; Dynein light chain Tctex-type 3; DYNLT3; Protein 91/23; RP23-256J17.2; RP3; T-complex-associated testis-expressed 1-like; Tcte1l; TCTEX1L.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 13kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DYNLT3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.[provided by RefSeq, Mar 2010]

Function:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis.

Subcellular Location:
Nucleus. Cytoplasm; cytoskeleton. Chromosome; centromere; kinetochore. Colocalizes with BUB3 at kinetochores specifically during prometaphase.

Similarity:
Belongs to the dynein light chain Tctex-type family.

Database links:

Entrez Gene: 6990 Human

Entrez Gene: 363448 Rat

Omim: 300302 Human

SwissProt: P51808 Human

Unigene: 446392 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

 

 

该基因编码一个亚类的动力蛋白轻链的成员。编码的蛋白质同质二聚并形成胞质动力蛋白运动蛋白复合物的轻链组分。这种蛋白对于结合动力蛋白与特定的物质(包括纺锤体检查点蛋白BUB3)可能是重要的。这种蛋白也可以独立于动力蛋白作为转录调节剂发挥作用。该基因的假基因可在2和20号染色体上找到。[ RefSeq,MAR 2010 ]