TIRAP monoclonal antibody, clone Sebi-1
产品名称: TIRAP monoclonal antibody, clone Sebi-1
英文名称: TIRAP monoclonal antibody, clone Sebi-1
产品编号: MAB3447
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rat monoclonal antibody raised against partial recombinant TIRAP.
- Immunogen:
- Recombinant GST fusion protein corresponding to amino acids 1-215 of human TIRAP.
- Host:
- Rat
- Reactivity:
- Human
- Specificity:
- Recognizes human TIRAP.
- Form:
- Liquid
- Isotype:
- IgG2a
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500)
Immunoprecipitation (1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Western Blot
- Immunoprecipitation
- Entrez GeneID:
- 114609
- Gene Name:
- TIRAP
- Gene Alias:
- FLJ42305,Mal,wyatt
- Gene Description:
- toll-interleukin 1 receptor (TIR) domain containing adaptor protein
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq
- Other Designations:
- MyD88 adapter-like protein,OTTHUMP00000179130,OTTHUMP00000179132,TIR domain-containing adapter protein,TIR domain-containing adaptor protein,Toll-interleukin 1 receptor (TIR) domain-containing adapter protein,Toll-interleukin 1 receptor (TIR) domain-conta
- Gene Pathway
- Related Disease
- Acute Lung Injury
- Bacteriuria
- Candidiasis, Oral
- Cardiovascular Diseases
- Chagas Cardiomyopathy
- Chronic Disease
- Cross Infection
- Cystitis
- Dermatitis, Atopic
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Genetic Predisposition to Disease
- HIV Infections
- Inflammation
- Leprosy
- Lupus Erythematosus, Systemic
- Malaria, Falciparum
- Pneumonia, Ventilator-Associated