Amyloid-beta monoclonal antibody, clone BAM01-抗体-抗体-生物在线
亚诺法生技股份有限公司（Abnova)
Amyloid-beta monoclonal antibody, clone BAM01

Amyloid-beta monoclonal antibody, clone BAM01

商家询价

产品名称： Amyloid-beta monoclonal antibody, clone BAM01

英文名称： Amyloid-beta monoclonal antibody, clone BAM01

产品编号： MAB3744

产品价格： null

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)
  • 联系人 :
  • 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
  • 邮编 : 11493
  • 所在区域 : 台湾
  • 电话 : +886-920**1152 点击查看
  • 传真 : 点击查看
  • 邮箱 : sales@abnova.com.tw
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of Beta amyloid.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 8-17 of human Beta amyloid.
  • Sequence:
  • SGYEVHHQKL
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Reacts with Beta-Amyloid. It reacts with a 4-5 KDa peptide (termed amyloid beta protein/ amyloid A4 or amyloid beta peptide) derived from the amyloid beta precursor protein. This antibody detects extracellular amyloid beta protein within senile plaques and vessel amyloid in formalin-fixed, paraffin-embedded brain of Alzheimer's and Lewy body disease.
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Storage Buffer:
  • In tissue culture supernatant (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(1:25-1:50)
    The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 351
  • Gene Name:
  • APP
  • Gene Alias:
  • AAA,ABETA,ABPP,AD1,APPI,CTFgamma,CVAP,PN2
  • Gene Description:
  • amyloid beta (A4) precursor protein
  • Gene Summary:
  • This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • A4 amyloid protein,amyloid beta A4 protein,amyloid-beta protein,beta-amyloid peptide,cerebral vascular amyloid peptide,peptidase nexin-II,protease nexin-II
  • Interactome
  • Gene Pathway

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