PSEN1 (C-term) Peptide-蛋白质/抗原/多肽-试剂-生物在线
亚诺法生技股份有限公司（Abnova)
PSEN1 (C-term) Peptide

PSEN1 (C-term) Peptide

商家询价

产品名称： PSEN1 (C-term) Peptide

英文名称： PSEN1 (C-term) Peptide

产品编号： P1930

产品价格： 0

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围： null

亚诺法生技股份有限公司（Abnova)
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  • Specification
  • Product Description:
  • This synthetic peptide sequence is selected from human PSEN1 construct and is used as the immunogen for PAB4892.
  • Sequence:
  • C terminus of Human PSEN1
  • Form:
  • Lyophilized with 100% acetonitrile
  • Storage Buffer:
  • Reconstitute with 100 uL deionized water for a final concentration of 1 mg/mL.
  • Storage Instruction:
  • Store at 4°C. For long term storage store at-20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product is for research use only. Not for use in diagnostics or therapeutics.
  • Applications
  • Blocking
  • Application Image
  • Blocking
  • Gene Information
  • Entrez GeneID:
  • 5663
  • Gene Name:
  • PSEN1
  • Gene Alias:
  • AD3,FAD,PS1,S182
  • Gene Description:
  • presenilin 1
  • Gene Summary:
  • Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene, the full-length nature of only some have been determined. [provided by RefSeq
  • Other Designations:
  • -

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