GCH1 polyclonal antibody (A01)
产品名称: GCH1 polyclonal antibody (A01)
英文名称: GCH1 polyclonal antibody (A01)
产品编号: H00002643-A01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant GCH1.
- Immunogen:
- GCH1 (NP_000152, 84 a.a. ~ 172 a.a) partial recombinant protein with GST tag.
- Sequence:
- ENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIV
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.9 KDa) .
- MSDS:
- Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 2643
- GeneBank Accession#:
- NM_000161
- Protein Accession#:
- NP_000152
- Gene Name:
- GCH1
- Gene Alias:
- DYT14,DYT5,GCH,GTP-CH-1,GTPCH1
- Gene Description:
- GTP cyclohydrolase 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. [provided by RefSeq
- Other Designations:
- guanosine 5'-triphosphate cyclohydrolase I
- Gene Pathway
- Related Disease
- Acute Disease
- Autistic Disorder
- Cardiovascular Diseases
- Cerebrovascular Disorders
- Chromosome Aberrations
- Chromosome Deletion
- Chronic Disease
- Coronary Artery Disease
- Coronary Disease
- Diabetes Mellitus, Type 2
- Diabetic Angiopathies
- Dystonia
- Dystonic Disorders
- Edema
- Genetic Predisposition to Disease
- Hypertension
- Labor Pain
- Low Back Pain
- Mental Retardation