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Anti-FEN1 Monoclonal Antibody

商家询价

产品名称： Anti-FEN1 Monoclonal Antibody

英文名称： Anti-FEN-1 Monoclonal Antibody

产品编号： K000145M

产品价格： null

产品产地：北京

品牌商标： Solarbio

更新时间： 2025-12-22T13:19:53

使用范围： WB

北京索莱宝科技有限公司

联系人 : 索莱宝-龚思雨
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产品详情

Anti-FEN1 Monoclonal Antibody
品牌：solarbio | 货号：K000145M

宿主 Mouse
英文名称 Anti-FEN1 Monoclonal Antibody
别名 FEN-1;MF1;RAD2;DNase IV;Flap endonuclease 1;flap structure endonuclease 1;hFEN 1;Maturation factor 1
应用 WB ICC
稀释比例 WB 1:1000. ICC 1:400.
蛋白分子量 36/43kDa
Gene ID 2237
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG1
免疫原 Purified recombinant human FEN1 protein fragments expressed in E.coli.
性状 液体
Subcellular Locations Mitochondrion Nucleus nucleolus nucleoplasm
Swiss Prot P39748
克隆号 7H8-F4-C11
克隆类型 Monoclonal Antibody
背景资料 The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate,thus passing the substrate from one enzyme to another.The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication.DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene.Therefore,secondary structure can deter the protective function of this protein,leading to site-specific trinucleotide expansions.[provided by RefSeq,Jul 2008]

宿主	Mouse
英文名称	Anti-FEN1 Monoclonal Antibody
别名	FEN-1;MF1;RAD2;DNase IV;Flap endonuclease 1;flap structure endonuclease 1;hFEN 1;Maturation factor 1
应用	WB ICC
稀释比例	WB 1:1000. ICC 1:400.
蛋白分子量	36/43kDa
Gene ID	2237
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG1
免疫原	Purified recombinant human FEN1 protein fragments expressed in E.coli.
性状	液体
Subcellular Locations	Mitochondrion Nucleus nucleolus nucleoplasm
Swiss Prot	P39748
克隆号	7H8-F4-C11
克隆类型	Monoclonal Antibody
背景资料	The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate,thus passing the substrate from one enzyme to another.The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication.DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene.Therefore,secondary structure can deter the protective function of this protein,leading to site-specific trinucleotide expansions.[provided by RefSeq,Jul 2008]