分子量：Calculated MW: 33kDa/34kDa/37kDa/39kDa
Observed MW: 45kDa

细胞定位：Cytoplasm

稀释方法：WB 1:500 - 1:2000

总结：This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.