CACNA2D1 polyclonal antibody
产品名称： CACNA2D1 polyclonal antibody
英文名称： CACNA2D1 polyclonal antibody
产品编号： PAB7294
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of CACNA2D1.
- Immunogen:
- A synthetic peptide corresponding to internal region of human CACNA2D1.
- Sequence:
- C-QEIFNKYNKDKKVR
- Host:
- Goat
- Theoretical MW (kDa):
- 123
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:16000)
Western Blot (0.03-0.1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Increased expression of the auxiliary beta(2)-subunit of ventricular L-type Ca(2)+ channels leads to single-channel activity characteristic of heart failure.
Hullin R, Matthes J, von Vietinghoff S, Bodi I, Rubio M, D'Souza K, Friedrich Khan I, Rottlander D, Hoppe UC, Mohacsi P, Schmitteckert E, Gilsbach R, Bunemann M, Hein L, Schwartz A, Herzig S.PLoS One. 2007 Mar 14;2(3):e292.
- Entrez GeneID:
- 781
- Protein Accession#:
- NP_000713.2
- Gene Name:
- CACNA2D1
- Gene Alias:
- CACNA2,CACNL2A,CCHL2A,MHS3
- Gene Description:
- calcium channel, voltage-dependent, alpha 2/delta subunit 1
- Omim ID:
- 114204
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
- Other Designations:
- H_DJ0560O14.1,WUGSC:H_DJ0560O14.1,calcium channel, L type, alpha 2 polypeptide,dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit
- Related Disease