分子量：Calculated MW: 56kDa
Observed MW: 57kDa

细胞定位：Cajal body, Cytoplasm, Nucleus, Nucleus speckle

稀释方法：IF 1:50 - 1:100

总结：The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants.