分子量：Calculated MW: 33kDa/34kDa/69kDa/71kDa
Observed MW: 72kDa

细胞定位：Cell membrane, Secreted, Single-pass type I membrane protein, Single-pass type I membrane protein

稀释方法：WB 1:500 - 1:2000

总结：This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.