NTRK1 Peptide
产品名称： NTRK1 Peptide
英文名称： NTRK1 Peptide
产品编号： P2729
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of NTRK1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y791 of human NTRK1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Expression of NGF in hepatocellular carcinoma cells with its receptors in non-tumor cell components.
Tokusashi Y, Asai K, Tamakawa S, Yamamoto M, Yoshie M, Yaginuma Y, Miyokawa N, Aoki T, Kino S, Kasai S, Ogawa K.Int J Cancer. 2005 Mar 10;114(1):39-45.
- 2.
- Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas.
Schulte JH, Schramm A, Klein-Hitpass L, Klenk M, Wessels H, Hauffa BP, Eils J, Eils R, Brodeur GM, Schweigerer L, Havers W, Eggert A.Oncogene. 2005 Jan 6;24(1):165-77.
- 3.
- Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer.
Frattini M, Ferrario C, Bressan P, Balestra D, De Cecco L, Mondellini P, Bongarzone I, Collini P, Gariboldi M, Pilotti S, Pierotti MA, Greco A.Oncogene. 2004 Sep 23;23(44):7436-40.
- Entrez GeneID:
- 4914
- Protein Accession#:
- NP_002520;P04629
- Gene Name:
- NTRK1
- Gene Alias:
- DKFZp781I14186,MTC,TRK,TRK1,TRKA,p140-TrkA
- Gene Description:
- neurotrophic tyrosine kinase, receptor, type 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq
- Other Designations:
- OTTHUMP00000038736,Oncogene TRK,high affinity nerve growth factor receptor,tyrosine kinase receptor A
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Asperger Syndrome
- Autistic Disorder
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Eating Disorders
- Edema
- Genetic Predisposition to Disease
- Hereditary Sensory and Autonomic Neuropathies
- Hyperparathyroidism, Secondary
- Kidney Failure, Chronic
- Leukemia, Myeloid, Acute
- Mental Disorders
- Neuroblastoma
- Social Perception
- Thyroid Diseases
- Thyroid Neoplasms