分子量：Calculated MW: 46kDa/109kDa
Observed MW: 120KDa/140KDa

细胞定位：Cell membrane, Cytoplasm, Single-pass type I membrane protein

稀释方法：WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

总结：This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.