分子量：Calculated MW: 27kDa
Observed MW: 36kDa

细胞定位：Endosome membrane, Lysosome membrane, Single-pass type I membrane protein

稀释方法：WB 1:500 - 1:2000

总结：HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.