RBP4 polyclonal antibody
产品名称： RBP4 polyclonal antibody
英文名称： RBP4 polyclonal antibody
产品编号： PAB14187
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of RBP4.
- Immunogen:
- A synthetic peptide corresponding to human RBP4.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- The rabbit anti-human Retinol-binding protein 4 detects specifically target derived from recombinant protein as well as cellular proteins at various concentrations. Cross reactivity with mouse and rat are expected from sequence similarity.
- Form:
- Liquid
- Storage Buffer:
- In PBS
- Storage Instruction:
- Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000-1:20000)
Western Blot (1:1000-1:5000)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects.
Graham TE, Yang Q, Bluher M, Hammarstedt A, Ciaraldi TP, Henry RR, Wason CJ, Oberbach A, Jansson PA, Smith U, Kahn BB.N Engl J Med. 2006 Jun 15;354(24):2552-63.
- 2.
- Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes.
Yang Q, Graham TE, Mody N, Preitner F, Peroni OD, Zabolotny JM, Kotani K, Quadro L, Kahn BB.Nature. 2005 Jul 21;436(7049):356-62.
- 3.
- Characterization of two post-translationally processed forms of human serum retinol-binding protein: altered ratios in chronic renal failure.
Jaconi S, Rose K, Hughes GJ, Saurat JH, Siegenthaler G.J Lipid Res. 1995 Jun;36(6):1247-53.
- Application Image
- Western Blot
- ELISA
- Entrez GeneID:
- 5950
- Protein Accession#:
- NM_006744
- Gene Name:
- RBP4
- Gene Alias:
- -
- Gene Description:
- retinol binding protein 4, plasma
- Omim ID:
- 180250
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq
- Other Designations:
- OTTHUMP00000020114,OTTHUMP00000020116,retinol-binding protein 4, interstitial,retinol-binding protein 4, plasma
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Cardiovascular Diseases
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Genetic Predisposition to Disease
- Glucose Intolerance
- Hyperlipidemias
- Hypertension
- Hypertriglyceridemia
- Insulin Resistance
- Metabolic Syndrome X
- Neoplasms
- Obesity
- Obesity
- Osteoporosis
- Prediabetic State