CD81 polyclonal antibody
产品名称： CD81 polyclonal antibody
英文名称： CD81 polyclonal antibody
产品编号： PAB16754
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CD81.
- Immunogen:
- A synthetic peptide corresponding to N-terminus 20 amino acids of human CD81.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Lateral organization of membrane proteins: tetraspanins spin their web.
Charrin S, le Naour F, Silvie O, Milhiet PE, Boucheix C, Rubinstein E.Biochem J. 2009 May 13;420(2):133-54.
- 2.
- Role of transmembrane 4 superfamily (TM4SF) proteins CD9 and CD81 in muscle cell fusion and myotube maintenance.
Tachibana I, Hemler ME.J Cell Biol. 1999 Aug 23;146(4):893-904.
- 3.
- Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29).
Mannion BA, Berditchevski F, Kraeft SK, Chen LB, Hemler ME.J Immunol. 1996 Sep 1;157(5):2039-47.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of CD81 in human lung tissue lysate with CD81 polyclonal antibody (Cat # PAB16754) at 1 ug/mL in (A) the absence and (B) the presence of blocking petide.
- Entrez GeneID:
- 975
- Protein Accession#:
- NP_004347
- Gene Name:
- CD81
- Gene Alias:
- S5.7,TAPA1,TSPAN28
- Gene Description:
- CD81 molecule
- Omim ID:
- 186845
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. [provided by RefSeq
- Other Designations:
- 26 kDa cell surface protein TAPA-1,CD81 antigen,CD81 antigen (target of antiproliferative antibody 1),target of antiproliferative antibody 1
- Gene Pathway
- Related Disease
- Atherosclerosis
- Carcinoma, Hepatocellular
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hepatitis C
- Hodgkin Disease
- Kidney Failure, Chronic
- Liver Neoplasms
- Lung Neoplasms
- Lymphoproliferative Disorders
- Multiple Myeloma
- Obesity
- Occupational Diseases
- Pulmonary Disease, Chronic Obstructive
- Urinary Bladder Neoplasms
- Waldenstrom Macroglobulinemia
- Werner syndrome