分子量：Calculated MW: 39kDa/40kDa
Observed MW: 36kDa/70kDa

细胞定位：Cell junction, Cell membrane, Early endosome, Late endosome, Lysosome, Multi-pass membrane protein

稀释方法：WB 1:500 - 1:1000

总结：This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.