产品概述：Purified recombinant protein of Human GDNF family receptor alpha like (GFRAL), with C-terminal His tag, secretory expressed in Sf9 cells, 20ug

蛋白长度：A DNA sequence from GoldORF clone, [GH42708V], encoding the region (19Ser-351Glu) of GFRAL.

表达系统：Sf9

种属：Human

标签类型：C-His

分子量：37.8 kDa

通用名：GFRAL

总结：Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.[UniProtKB/Swiss-Prot Function]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：50 mM Tris.HCl, pH 8.0, 150 mM glycine, 10% glycerol

别名：bA360D14.1; C6orf144; GRAL; UNQ9356