产品概述：Purified recombinant protein of Human MG53, Met1-Asp270, expressed in E. coli, 50ug

蛋白长度：A DNA sequence encoding the region Met1-Asp270 of MG53

表达系统：E. coli

种属：Human

标签类型：Tag Free

分子量：29.6 kDa

通用名：TRIM72

总结：Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).[UniProtKB/Swiss-Prot Function]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 85% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：PBS, 10%glycerol

别名：MG53