FITC标记的黑色素瘤相关抗原B2抗体
产品名称： FITC标记的黑色素瘤相关抗原B2抗体
英文名称： Anti-MAGEB2/FITC
产品编号： HZ-6822R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-MAGEB2/FITC Conjugated antibody
FITC标记的黑色素瘤相关抗原B2抗体
| 英文名称 | Anti-MAGEB2/FITC |
| 中文名称 | FITC标记的黑色素瘤相关抗原B2抗体 |
| 别 名 | Cancer/testis antigen 3.2; CT3.2; DAM6; DSS AHC critical interval MAGE superfamily 6; DSS/AHC critical interval gene, from MAGE superfamily, 6; MAGE B2 antigen; MAGE XP 2; Mage-b2; Mage-rs2; melanoma antigen family B, 2; Melanoma antigen, family B, 1; Melanoma associated antigen B2; Smage-2 protein; Smage2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 肿瘤细胞生物标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MAGEB2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]. Function: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Subunit: Interacts with TRIM28. Tissue Specificity: Expressed in testis and placenta, and in a significant fraction of tumors of various histologic types. Similarity: Contains 1 MAGE domain. Database links: Entrez Gene: 4113 Human Omim: 300098 Human SwissProt: O15479 Human Unigene: 113824 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applicatio |
This is of the mageb基因家族成员的基因。of this the members have their家庭全部编码序列外显子和并置在the last，the编码蛋白序列标识显示50到68% to each other。第一外显子promoters and the of the mageb基因considerable variability that the show of this，suggesting存在基因家族enables the same function to be different表达的转录控制下。This is the DSS（定域在基因剂量敏感的性反转的临界区域。它是表达在睾丸和胎盘中的重要组分，和在各种肿瘤histological of types of。茶是由mageb基因染色体p21 xp22丛生。[提供]序列模式，2008年7月。