UBR2 monoclonal antibody (M01A), clone 4G4
产品名称: UBR2 monoclonal antibody (M01A), clone 4G4
英文名称: UBR2 monoclonal antibody (M01A), clone 4G4
产品编号: H00023304-M01A
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant UBR2.
- Immunogen:
- UBR2 (NP_056070, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCG
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In ascites fluid
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- MSDS:
- Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of UBR2 expression in transfected 293T cell line by UBR2 monoclonal antibody (M01A), clone 4G4.
Lane 1: UBR2 transfected lysate(50 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Application Image
- Western Blot (Transfected lysate)
- enlarge
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 23304
- GeneBank Accession#:
- NM_015255
- Protein Accession#:
- NP_056070
- Gene Name:
- UBR2
- Gene Alias:
- C6orf133,DKFZp686C08114,KIAA0349,MGC71112,RP3-392M17.3,bA49A4.1,dJ242G1.1,dJ392M17.3
- Gene Description:
- ubiquitin protein ligase E3 component n-recognin 2
- Omim ID:
- 609134
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM
- Other Designations:
- OTTHUMP00000016403,OTTHUMP00000016405,OTTHUMP00000039767,OTTHUMP00000039768,ubiquitin ligase E3 alpha-II
- Related Disease