GAD2 polyclonal antibody
产品名称： GAD2 polyclonal antibody
英文名称： GAD2 polyclonal antibody
产品编号： PAB6778
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of GAD2.
- Immunogen:
- A synthetic peptide corresponding to human GAD2.
- Sequence:
- C-TLEDNEERMSRLSK
- Host:
- Goat
- Theoretical MW (kDa):
- 65.4, 65.4
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:32000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Is glutamate decarboxylase 2 (GAD2) a genetic link between low birth weight and subsequent development of obesity in children?
Meyre D, Boutin P, Tounian A, Deweirder M, Aout M, Jouret B, Heude B, Weill J, Tauber M, Tounian P, Froguel P.J Clin Endocrinol Metab. 2005 Apr;90(4):2384-90. Epub 2005 Jan 25.
- Entrez GeneID:
- 2572
- Protein Accession#:
- NP_000809.1
- Gene Name:
- GAD2
- Gene Alias:
- GAD65,MGC161605,MGC161607
- Gene Description:
- glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- Omim ID:
- 138275
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq
- Other Designations:
- Glutamate decarboxylase-2 (pancreas),OTTHUMP00000019335,OTTHUMP00000019336,glutamate decarboxylase 2,glutamate decarboxylase 2 (pancreatic islets and brain, 65kD)
- Related Disease
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Anorexia Nervosa
- Anxiety Disorders
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Birth Weight
- Body Weight
- Bulimia
- Cardiovascular Diseases
- Cleft Lip
- Cleft Palate
- Cognition
- Depressive Disorder
- Depressive Disorder, Major
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Disease Models, Animal