分子量：Calculated MW: 22kDa/32kDa
Observed MW: 50kDa

细胞定位：Cytoplasm, Peripheral membrane protein, Preautophagosomal structure membrane

稀释方法：WB 1:500 - 1:2000
IHC 1:50 - 1:100

总结：The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.