FITC标记的半胱氨酰白三烯受体2型抗体
产品名称： FITC标记的半胱氨酰白三烯受体2型抗体
英文名称： Anti-CysLT2/FITC
产品编号： HZ-20055R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-CysLT2/FITC Conjugated antibody
FITC标记的半胱氨酰白三烯受体2型抗体
| 英文名称 | Anti-CysLT2/FITC |
| 中文名称 | FITC标记的半胱氨酰白三烯受体2型抗体 |
| 别 名 | CLTR2_HUMAN; CYSLT2; CYSLT2R; CYSLTR 2; CysLTR2; Cysteinyl leukotriene CysLT2 receptor; Cysteinyl leukotriene receptor 2; G protein coupled receptor; G protein coupled receptor GPCR21; G protein coupled receptor HG57; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57; GPCR; HG57; hGPCR21; HPN321; PSEC0146. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CysLT2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. [provided by RefSeq, Jul 2008] Function: Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4. Subcellular Location: Cell membrane. Tissue Specificity: Widely expressed, with highest levels in the heart, placenta, spleen, peripheral blood leukocytes and adrenal gland. In lung, expressed in the interstitial macrophages, and slightly in smooth muscle cells. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 57105 Human Omim: 605666 Human SwissProt: Q9NS75 Human Unigene: 253706 Human Unigene: 614318 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
半胱氨酰白三烯LTC4、LTD4和LTE4是支气管哮*的重要介质。药理学研究已经确定半胱氨酸白三烯至少激活2个受体，该蛋白由该基因和CYSLTR1编码。这个编码的受体是G蛋白偶联受体超家族的成员。它似乎在内分泌和心血管系统中起着重要作用。[ RefSeq，JUL 2008 ]