分子量：Calculated MW: 44kDa
Observed MW: 44kDa

细胞定位：Membrane, Multi-pass membrane protein

稀释方法：WB 1:1000 - 1:2000

总结：The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.