Murine & Rat Growth Factors & Cytokines
Recombinant Rat TPO


 
 
Synonyms :
Thrombopoietin, Megakaryocyte colony-stimulating factor, c-MPL Ligand, MGDF
Description :
TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant rat TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein.
Catalog #:
400-34
Source :
E.coli
Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Biological Activity :
Determined by its ability to stimulate the proliferation of human MO7e cells. The expected B>ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
AA Sequence :
SPVPPACDPR LLNKLLRDSY LLHSRLSQCP DVNPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPPQGRTTA HKDPSALFLS LQQLLRGKVR FLLLVEGPAL CVRRTLPTTA VPSRTSQLLT LNKF 
PubMed Link :
Rat TPO
Country of Origin :
USA
 
 
Size A
2μg
$80 
 
 
Size B
10μg
$195 
 
 
Size C
1mg
$4300 
 
 
 
 
Special Sizes: 
Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.
 
Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.