FITC标记的1号染色体开放阅读框73抗体
产品名称： FITC标记的1号染色体开放阅读框73抗体
英文名称： Anti-INTS7/C1orf73/FITC
产品编号： HZ-14337R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-INTS7/C1orf73/FITC Conjugated antibody
FITC标记的1号染色体开放阅读框73抗体
| 英文名称 | Anti-INTS7/C1orf73/FITC |
| 中文名称 | FITC标记的1号染色体开放阅读框73抗体 |
| 别 名 | INTS7; 5930412E23Rik; DKFZP434B168; C1orf73; Chromosome 1 open reading frame 73; chunp6916; DKFZp434B168; FLJ10736; FLJ12447; Int7; INT7_HUMAN; integrator complex subunit 7; INTS7; Ints7 integrator complex subunit 7; OTTHUMP00000035211; RGD1308014. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 107kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human INTS7/C1orf73 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] Function: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Plays a role in DNA damage response (DDR) signaling during the S phase. Subunit: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12. Interacts with NABP2. Subcellular Location: Nucleus. Chromosome. Localizes to sites of DNA damage in a H2AX-independent manner. Similarity: Belongs to the Integrator subunit 7 family. Database links: Entrez Gene: 25896 Human Entrez Gene: 421374 Chicken Omim: 611350 Human SwissProt: Q5ZL91 Chicken SwissProt: Q1RMS6 Cow SwissProt: Q9NVH2 Human Unigene: 369285 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码积分器复合体的亚基。整合子复合物与RNA聚合酶II的C端结构域相关联，介导小核RNA U1和U2的3′端加工。另一种编码多个异构体的剪接转录变体已被观察到该基因。[ RefSeq提供，DEC 2010 ]