CD36 monoclonal antibody, clone CLB-IVC7
产品名称: CD36 monoclonal antibody, clone CLB-IVC7
英文名称: CD36 monoclonal antibody, clone CLB-IVC7
产品编号: MAB5275
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD36.
- Immunogen:
- Native purified CD36 from human monocytes.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- The monoclonal antibody is directed against the CD36 antigen (a 90kD glycoprotein). The antigen is also called GP IV or GP IIIb. It is expressed on human platelets. The monoclonal antibody reacts with platelets, monocytes, macrophages, erythroblasts and weak with B-cells. In immunohistology the monoclonal antibody reacts with some endothelial cells, adipocytes and the granular layer of the skin. The GP IV (GP IIIb) molecule has been shown to function as thrombospondin receptor on platelets and monocytes and as a receptor for Plasmodium falciparum infected erythrocytes.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In 20 mM Tris, 150 mM NaCl, pH 8.0 (10 mg BSA, 0.1% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Immunohistochemistry (Frozen sections)
- Immunofluorescence
- Flow Cytometry
- Entrez GeneID:
- 948
- Gene Name:
- CD36
- Gene Alias:
- CHDS7,FAT,GP3B,GP4,GPIV,PASIV,SCARB3
- Gene Description:
- CD36 molecule (thrombospondin receptor)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- CD36 antigen,CD36 antigen (collagen type I receptor, thrombospondin receptor),PAS-4 protein,cluster determinant 36,fatty acid translocase,glycoprotein IIIb,leukocyte differentiation antigen CD36,platelet glycoprotein IV,scavenger receptor class B, member
- Related Disease
- Anemia
- Angina Pectoris
- Atherosclerosis
- Atherosclerosis
- Calcinosis
- Cardiovascular Diseases
- Colon cancer
- Colorectal Neoplasms
- Coronary Artery Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Genetic Predisposition to Disease
- Hepatitis, Toxic
- Hypertension
- Insulin Resistance
- Kidney Failure, Chronic
- Macular Degeneration