MLXIPL Pre-design Chimera RNAi
产品名称： MLXIPL Pre-design Chimera RNAi
英文名称： MLXIPL Pre-design Chimera RNAi
产品编号： H00051085-R02
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- Specification
- Product Description:
- Homo sapiens MLX interacting protein-like (MLXIPL), transcript variant 2, mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_032952
- Target Region:
- Coding sequence
- Note:
- Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. -
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 51085
- Gene Name:
- MLXIPL
- Gene Alias:
- CHREBP,MIO,MONDOB,WBSCR14,WS-bHLH,bHLHd14
- Gene Description:
- MLX interacting protein-like
- Omim ID:
- 605678
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. [provided by RefSeq
- Other Designations:
- Mlx interactor,OTTHUMP00000160457,OTTHUMP00000160458,WS basic-helix-loop-helix leucine zipper protein,Williams Beuren syndrome chromosome region 14,carbohydrate response element binding protein,carbohydrate-responsive element-binding protein
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Brain Ischemia
- Breast cancer
- Breast Neoplasms
- Cardiovascular Diseases
- Coronary Artery Disease
- Dementia
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Genetic Predisposition to Disease
- Hypertriglyceridemia
- Insulin Resistance
- Lipid Metabolism Disorders
- Metabolic Syndrome X
- Neoplasms
- Obesity
- Obesity
- Osteoporosis